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Join the HJF Team!
HJF is seeking Postdoctoral Fellow to explore novel therapeutics of metastatic breast cancer to support the lab of Dr. Geeta Upadhyay within the Department of Pathology located at the Uniformed Services University (USU) in Bethesda, MD. HJF provides scientific, technical and programmatic support services to the Department of Pathology.
About USUHS: The mission of the USUHS is to educate, train, and comprehensively prepare uniformed services health professionals, scientists, and leaders to support the Military and Public Health Systems, the National Security and National Defense Strategies of the United States, and the readiness of our Uniformed Services. USUHS is integral part of F. Edward Hbert School of Medicine. Within campus, we collaborated with Armed Forces Radiobiology Research Institute and with Murtha Cancer Center, Walter Reed, capital Breast care project. USUHS is located in close proximity to National Institute of health, providing opportunities for cross campus collaboration. More info: https://www.usuhs.edu/
Core facilities at USUHS: https://www.usuhs.edu/research/core-facilities
About Geeta Upadhyay: Dr. Upadhyay recently joined USUHS faculty as tenure track faculty. Dr. Upadhyay received her training at Harvard, NCI, UTHSCSA, Georgetown University. Her research is focused on biomarker discover, novel drug development and drug resistance in breast cancer. Click here for a complete list of publications: https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/42266779/?sort=date&direction=descending
Project Description: The postdoctoral candidate will have the opportunity to conduct cutting edge research on novel therapeutics including opportunity to explore immunotherapy for metastatic breast cancer. Our lab is focused on understanding the novel role of human Ly6 genes in drug resistance, cancer progression and metastasis. Please see following publication for more detailed account of the research projects.
Upadhyay G, Yin Y, Yuan H, Li X, Derynck R, Glazer RI. Stem cell antigen-1 enhances tumorigenicity by disruption of growth differentiation factor-10 (GDF10)-dependent TGF-beta signaling. Proc. Natl. Acad. Sci. U.S.A., 108, 7820–7825 (2011). PMID: 21518866.
AlHossiny M, Luo L, Frazier WR, Steiner N, Gusev Y, Kallakury B, Glasgow E, Creswell K, Madhavan S, Kumar R, Upadhyay G. Lymphocyte antigens 6 complex K/E-transforming growth factor-beta axis promotes breast cancer tumorigenesis. Cancer Res., 76, 3376–3386 (2016). PMID: 27197181.
Luo L, McGarvey P, Madhavan S, Kumar R, Gusev Y, Upadhyay G. Lymphocyte antigens 6 complex gene family members drive tumorigenesis. Oncotarget, 7, 11165–11193 (2016). PMID: 2686284
Required Knowledge, Skills, and Abilities: Knowledge of appropriate scientific area; ability to analyze and interpret data.
Minimum Education/Training Requirements: PhD in a related scientific discipline
Minimum Experience: 0 to 4 years directly related research experience
Physical Capabilities: Requires long periods of sitting and standing; handling of various chemicals, ability to work weekend/evenings
Supervisory Responsibilities/Controls: Provides guidance to lower level laboratory staff.
Work Environment: Laboratory environment; may involve working with biohazardous materials; may require working evenings and weekends
Background: Eligibility to obtain a Common Access Card (CAC); eligibility to obtain and hold a Public Trust background.
HJF is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.
Any qualifications to be considered as equivalents, in lieu of stated minimums, require the prior approval of the Chief Human Resources Officer.