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Join the HJF Team!
Scientist position is available in the laboratory of Dr. Kathleen Pratt (https://www.usuhs.edu/faculty-staff/kathleen-p-pratt-phd) at the Uniformed Services University of the Health Sciences (USU) in Bethesda, MD. Motivated individuals with a recent PhD in immunology, biochemistry, bioinformatics, or a related field, or with an MD, are encouraged to apply. Experience in subcloning, expressing and purifying proteins from various expression systems and/or or a background in immunoprofiling of T and B cells from humans or mouse models, are considered a strong plus. The position is funded for 3+ years and will be filled at the postdoctoral fellow or research associate level, depending on qualifications. This research project will expand our novel approaches to induce immune tolerance to a therapeutic protein drug, coagulation factor VIII. Techniques will include tissue culture, flow cytometry, ELISPOT/Fluorospot assays, TCR repertoire profiling (including single-cell methods), RNASeq and transcriptomics analysis, molecular biology and protein chemistry. Our goal is to understand the mechanisms governing making and breaking of peripheral tolerance to protein therapeutics, and to translate research results to improve clinical outcomes for patients.
USU is in Bethesda, MD, directly across the street from the NIH, and is thus part of an extraordinarily vibrant local biomedical research community. Our research projects take advantage of recently established Core facilities for Nextgen sequencing and Bioinformatics analysis. USU has a strongly collaborative environment, with weekly Immunology data club and journal club meetings, as well as regular research seminars featuring local and invited speakers.
HJF is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.
Any qualifications to be considered as equivalents, in lieu of stated minimums, require the prior approval of the Chief Human Resources Officer.