Research Associate II (Surgical Critical Care Initiative)

Updated: May 18, 2018
Job ID: 213777
Status: Full-Time
Regular/Temporary: Regular
Location: Bethesda, MD, United States

Join the HJF Team!

HJF is seeking a Research Associate II for the within the Walter Reed/ USU Department of Surgery in support of the Surgical Critical Care Initiative (SC2i)The Research Associate will design, plan and conduct research in support of the Surgical Critical Care Initiative’s research efforts. The successful candidate will perform complex, non-standard tests (GxP and non-GxP) in the study of wound repair, stem cell biology, traumatic brain injury, and biological responses in critical patient care. Training of junior staff is also an essential component. This position may require working evenings or weekends depending on experimental or clinical study protocol requirements.

Responsibilities:

  • Perform complex, non-standard, GCLP (GCP, GLP)/GMP/non-GxP tests and experiments in integrative life sciences.  This may include cell separation techniques, cell activation and proliferation studies, molecular biology and protein studies, flow cytometric techniques, multiplex ELISA and DNA/RNA isolation and analysis.
  • Experience with xMAP technology and Luminex platforms (MAGPIX, Luminex 100/200, and/or FLEXMAP 3D) preferred.
  • Proficiency and working knowledge of molecular and cell biology techniques as utilized in a cellular immunology laboratory including: Cell separation, cell culture, subcellular analysis, RNA and DNA extraction and purification, RT-PCR, hybridization assays, flow cytometry, immunoprecipitation, and multiplex ELISA analysis.
  • Perform instrument assay validations and equivalencies in compliance with GCLP/CAP/CLIA requirements.
  • Design and carry out experiments as well as process and interpret experimental data. Prepare accurate and timely research reports using computerized data analysis programs for investigators as required.
  • Perform biorepository processing of clinical samples in compliance with GCLP/CLIA requirements, maintain biorepository sample inventory for various studies, and ship Category B Biological Substances out of state per IATA/ICAO regulations.
  • Plan and perform instrument and assay validations in compliance with GCLP/CLIA requirements.
  • Train the in-lab functions of junior research assistants, surgical residents, students and guest researchers.
  • Maintain all required Department of Defense training courses that are pertinent to this position and adhere to legal, professional and ethical codes with respect to patient confidentiality and privacy (HIPAA/PHI/PII)
  • Present data at departmental and national meetings as required.

Supportive Duties as Required:

  • Adapt and implement new procedures and methods into the laboratory routine, adjust or write SOPs/lab or batch records.
  • Work with the data management and analytics team to ensure laboratory data are complete and stored in appropriate databases in compliance with GCLP/CLIA requirements.
  • Help maintain laboratory, computer systems, and equipment to ensure compliance with GCLP/CLIA requirements.
  • Work with QAU (Quality Assurance Unit) to ensure lab/instrument/assay documentations are compliant with GCLP/CLIA requirements.

Required Knowledge, Skills, and Abilities:  Prior experience in cell culture, cellular immunology, and molecular biology is necessary; knowledge and experience in GxP analytical testing (regulations and practice); ability to work adeptly, accurately, and efficiently to meet project deadlines; ability to quickly become proficient in new research techniques and incorporate into the regulated laboratory routine; good communication and analytical skills; ability to work well within a team- and goal-oriented work environment; working knowledge of Microsoft Office to include Outlook, Access, PowerPoint, Excel, and Word.

Minimum Education/Training Requirements: Master's degree

Minimum Experience:  10 years (6 years with Master’s) laboratory experience and at least 2 years of experience in regulated testing with a CRO preferred. Experience in a GxP setting required

Physical Capabilities: Requires long periods of sitting and standing; handling of various chemicals; requires delivery of biological samples to local laboratories.

Background:  Must be a U.S. citizen and be able to obtain Department of Defense Security Clearance (Secret Clearance) and a Common Access Card (CAC).

Supervisory Responsibilities/Controls: Will work directly with civilian, military, and contract laboratory personnel.

Work Environment: GCLP/CLIA-compliant clinical research laboratory; GMP experience will be similar.

HJF is an equal opportunity and affirmative action employer.  All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other status protected by law.

Any qualifications to be considered as equivalents, in lieu of stated minimums, require the prior approval of the Vice President of Human Resources.

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